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Published versions of the SPIRIT 2025 and CONSORT 2025 Statements

To reach the widest possible audience, the SPIRIT 2025 and CONSORT 2025 Statements were both published simultaneously in five leading medical journals. The content of each Statement is identical across all five journals. When citing SPIRIT 2025 or CONSORT 2025, you can cite any of the versions linked below.

SPIRIT 2025

Read the SPIRIT 2025 Statement in the BMJ

Cite as: Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. BMJ. 2025; [x:xx. doi: xxxxxxxxxx]

Read the SPIRIT 2025 Statement in JAMA

Cite as: Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. JAMA. 2025; [x:xx. doi: xxxxxxxxxx]

Read the SPIRIT 2025 Statement in The Lancet

Cite as: Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. Lancet. 2025; [x:xx. doi: xxxxxxxxxx]

Read the SPIRIT 2025 Statement in Nature Medicine

Cite as: Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. Nat Med. 2025; [x:xx. doi: xxxxxxxxxx]

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Read the SPIRIT 2025 Statement in PLoS Medicine

Cite as: Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. PLoS Med. 2025; [x:xx. doi: xxxxxxxxxx]

Coming soon

CONSORT 2025

Read the CONSORT 2025 Statement in the BMJ

Cite as: Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. BMJ. 2025; 388:e081123. https://dx.doi.org/10.1136/bmj-2024-081123

Read the CONSORT 2025 Statement in JAMA

Cite as: Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. JAMA. 2025. https://dx.doi.org/10.1001/jama.2025.4347

Read the CONSORT 2025 Statement in the The Lancet

Cite as: Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. Lancet. 2025. https://doi.org/10.1016/S0140-6736(25)00672-5

Read the CONSORT 2025 Statement in Nature Medicine

Cite as: Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. Nat Med. 2025. https://doi.org/10.1038/s41591-025-03635-5

Read the CONSORT 2025 Statement in PLoS Medicine

Cite as: Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. PLoS Med. 2025; 22(4): e1004587. https://doi.org/10.1371/journal.pmed.1004587

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The 2025 update of SPIRIT and CONSORT, and this website, are funded by the MRC-NIHR: Better Methods, Better Research [MR/W020483/1]. The views expressed are those of the authors and not necessarily those of the NIHR, the MRC, or the Department of Health and Social Care.

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